Actin dynamics drive cell-like membrane deformation
نویسندگان
چکیده
منابع مشابه
Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions.
Embryonic development and adult tissue homeostasis require precise information exchange between cells and their microenvironment to coordinate cell behavior. A specialized class of ultra-long actin-rich filopodia, termed cytonemes, provides one mechanism for this spatiotemporal regulation of extracellular cues. We provide here a mechanism whereby the stem-cell marker Lgr5, and its family member...
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ژورنال
عنوان ژورنال: Nature Physics
سال: 2019
ISSN: 1745-2473,1745-2481
DOI: 10.1038/s41567-019-0464-1